BRAF V600E Rabbit anti-Human, Clone:RM8, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-333-288-Each-of-1 | In Stock | ₹ 85,351.00 |
89-333-288 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,351.00
GST (18%): ₹ 15,363.18
Total Price: ₹ 1,00,714.18
Antigen
BRAF V600E
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunocytochemistry (2ug/mL-10ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5ug/mL-5ug/mL)Western Blot (0.5ug/mL-2ug/mL)The optimal working dilution should be determined by the end user.
Gene
BRAF
Host Species
Rabbit
Quantity
100 μg
Test Specificity
This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM8
Description
v-raf murine sarcoma viral oncogene homolog B1
Formulation
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Gene Alias
B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1
Immunogen
A peptide corresponding to human BRAF V600E mutant.
Gene ID (Entrez)
673
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases
- This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
- Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance
- Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
- A pseudogene, which is located on chromosome X, has been identified for this gene
- [provided by RefSeq]