Home Products Antibodies Primary Antibodies 89 333 295
89-333-295

ANPEP Rabbit anti-Human, Clone:RM314, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-333-295-Each-of-1 In Stock ₹ 49,039.00

89-333-295 - Each of 1

₹ 49,039.00

In Stock

Quantity

1

Base Price: ₹ 49,039.00

GST (18%): ₹ 8,827.02

Total Price: ₹ 57,866.02

Antigen

ANPEP

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)Western Blot (1:1000-2000)The optimal working dilution should be determined by the end user.

Gene

ANPEP

Host Species

Rabbit

Quantity

100 μL

Test Specificity

This antibody reacts to human CD5.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM314

Description

alanyl (membrane) aminopeptidase

Formulation

In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)

Gene Alias

APN, CD13, LAP1, PEPN, gp150, p150

Immunogen

A peptide corresponding to C-terminus of human ANPEP.

Gene ID (Entrez)

290

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes
  • In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases
  • Its function in proximal tubular epithelial cells and other cell types is less clear
  • The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily
  • Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical
  • The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS
  • Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections
  • Defects in this gene appear to be a cause of various types of leukemia or lymphoma
  • [provided by RefSeq]