89-933-622

BAX Mouse anti-Human, Clone: BAX/962, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-933-622-Each-of-1 In Stock ₹ 67,017.00

89-933-622 - Each of 1

₹ 67,017.00

In Stock

Quantity

1

Base Price: ₹ 67,017.00

GST (18%): ₹ 12,063.06

Total Price: ₹ 79,080.06

Antigen

BAX

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determ

Gene Alias

BCL2L4

Host Species

Mouse

Purification Method

Protein A/G purification

Regulatory Status

RUO

Gene ID (Entrez)

581

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Clone

BAX/962

Description

Mouse monoclonal antibody raised against full length recombinant human BAX.

Formulation

In 10mM PBS (0.05% BSA, 0.05% sodium azide).

Gene Symbols

BAX

Immunogen

Recombinant protein corresponding to full length human BAX.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein.

Content And Storage

Store at 4°C.

Isotype

IgG1

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Description

  • The protein encoded by this gene belongs to the BCL2 protein family
  • BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities
  • This protein forms a heterodimer with BCL2, and functions as an apoptotic activator
  • This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c
  • The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis
  • Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene
  • [provided by RefSeq]