89-933-724

CASP3 Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-933-724-Each-of-1 In Stock ₹ 68,797.00

89-933-724 - Each of 1

₹ 68,797.00

In Stock

Quantity

1

Base Price: ₹ 68,797.00

GST (18%): ₹ 12,383.46

Total Price: ₹ 81,180.46

Antigen

CASP3

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against recombinant human CASP3.

Formulation

In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

Gene Symbols

CASP3

Immunogen

Recombinant protein corresponding to amino acids of human CASP3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Immunohistochemistry (1:500-1:1000) Western Blot (1:100-1:250) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene Alias

CPP32/CPP32B/SCA-1

Host Species

Rabbit

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

836

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
  • This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
  • It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease
  • Alternative splicing of this gene results in two transcript variants that encode the same protein
  • [provided by RefSeq] Sequence: HGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDL