89-933-734
CCNE1 Mouse anti-Human, Mouse, Clone: 5F8C5, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-933-734-Each-of-1 | In Stock | ₹ 85,440.00 |
89-933-734 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,440.00
GST (18%): ₹ 15,379.20
Total Price: ₹ 1,00,819.20
Antigen
CCNE1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
ELISA (1:10000) Flow Cytometry (1:200-1:400) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Gene Alias
CCNE
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Applications
ELISA, Flow Cytometry, Western Blot
Clone
5F8C5
Description
Mouse monoclonal antibody raised against partial recombinant human CCNE1.
Formulation
In PBS (0.05% sodium azide)
Gene Symbols
CCNE1
Immunogen
Recombinant protein corresponding to amino acids 307-410 of human CCNE1.
Regulatory Status
RUO
Gene ID (Entrez)
898
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Related Products
Description
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
- Cyclins function as regulators of CDK kinases
- Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
- This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition
- This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase
- Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis
- This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB
- Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described
- Two additional splice variants were reported but detailed nucleotide sequence information is not yet available
- [provided by RefSeq]