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A21272

HuC/HuD Monoclonal Antibody (16A11), Biotin, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 A21272-Each-of-1 In Stock ₹ 44,500.00

A21272 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

HuC/HuD

Classification

Monoclonal

Conjugate

Biotin

Gene

ELAVL3

Gene Alias

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV like neuron-specific RNA binding protein 3; ELAV like neuron-specific RNA binding protein 4; ELAV like RNA binding protein 4; elavC; ELAVL3; elavl3 protein; elavl4; ELAV-like protein 3; ELAV-like protein 4; elav-related C; elav-related D; elrc; elrd; embryonic lethal, abnormal vision-related C; embryonic lethal, abnormal vision-related D; etID309927.3; Hu antigen C; Hu antigen D; hu-antigen C; Hu-antigen D; HuC; HUCL; hud; id:ibd1248; Paraneoplastic cerebellar degeneration-associated antigen; paraneoplastic encephalomyelitis antigen HuD; Paraneoplastic limbic encephalitis antigen 21; PLE21; PNEM; protein elrD; ribonucleoprotein; RNA-binding protein HuD; wu:fb77b03; wu:fc24h01; zHuC

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

1995, 1996

Content And Storage

-20°C

Form

Lyophilized

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

16A11

Formulation

antibody with no preservative

Gene Accession No.

P26378, Q14576

Gene Symbols

ELAVL3, ELAVL4

Immunogen

Human HuC/HuD neuronal protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Description

  • This antibody recognizes the Elav family members HuC, HuD and Hel-N1 neuronal proteins
  • It does not recognize HuR, another Elav family member that is present in all proliferating cells
  • The antibody has been shown to specifically label neuronal cells in zebrafish, chick, canaries, and humans, and is likely to label neuronal cells in most vertebrate species
  • Labeling is visible early in development, at about the time that the neurons leave the mitotic cycle
  • Storage and reconstitution: Upon receipt, lyophilized antibodies should be stored desiccated at -20oC or lower
  • When properly stored, these products are stable for at least one year
  • To prepare stock solution, reconstitute the antibody in 0.5-1 mL PBS, pH 7.4, containing 1% BSA
  • Store the solution for up to two weeks at 4oC with the addition of 2mM sodium azide
  • For longer storage, divide solutions into single-use aliquots and freeze at -20oC, avoidig freeze/thaw cycles
  • For best results in immunohistochemistry, antigen retrieval is required
  • Use 50mM Tris, pH 8.0, for 30 minutes
  • The biotin-XX labeled antibody can be detected by using fluorescently labeled avidin, streptavidin or NeutrAvidin conjugates
  • Anti-Hu antibodies were originally isolated from a patient with paraneoplastic encephalomyelitis, a rare condition of selective neural tissue injury associated with small cell lung carcinoma
  • The antibodies bind specifically to antigens present exclusively in neuronal cells and are thus useful as markers of neuronal cells in tissue
  • The Hu antigen is an RNA-binding protein of the embryonic lethal abnormal visual (Elav) family.