ABC1444MI
MilliporeSigma™ Sorting Nexin-11, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC1444MI-Each-of-1 | In Stock | ₹ 40,292.08 |
ABC1444MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
Sorting Nexin-11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Snx11
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody reacts with both human and murine sorting nexin-11. The immunogen sequence is also present in human spliced isoform 2 and rat sorting nexin-11.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in PBS with 0.05% Sodium Azide.
Gene Accession No.
Q91WL6
Immunogen
Linear peptide corresponding to an internal sequence from the C-terminal half of mouse sorting nexin-11.
Quantity
100 μL
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_001156861
Target Species
Human
Related Products
Description
- Sorting nexin-11 (UniProt Q91WL6) is encoded by the Snx11 gene (Gene ID 74479) in murine species
- Sorting nexins (SNXs) are involved in diverse intracellular endosomal traffickings
- Their phox homology (PX) domain binds certain phosphatidylinositols (PIs) and mediates their recruitment to PI-rich vesicles
- Most SNXs contain additional recognizable domains and are referred to as SNX PX-BAR or SNX PX-other, while SNX3, SNX10, SNX11, SNX12, SNX22, and SNX24 contain only the PX domain and are referred to as SNX PX
- SNX11 is found to contain a novel PXe domain (a.a
- 16-132 of human and mouse SNX11) with two additional α-helices next to the conventional PX domain structure composed of three β-strands and three α-helices
- F2RL1 (a.k.a
- PAR2) is a protease-activated GPCR highly expressed throughout the central and the peripheral nervous system
- F2RL1 is reported to translocate from the plasma membrane to nucleus upon stimulation via a microtubule-dependent shuttle machinery that requires sorting nexin 11.