PAPPA Monoclonal Antibody (PAPP A 1-24), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS0062402-Each-of-1 | In Stock | ₹ 88,065.50 |
ABS0062402 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 88,065.50
GST (18%): ₹ 15,851.79
Total Price: ₹ 1,03,917.29
Antigen
PAPPA
Classification
Monoclonal
Concentration
0.92 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
Q13219
Gene Symbols
PAPPA
Immunogen
Purified human PAPP-A.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone
PAPP A 1-24
Conjugate
Unconjugated
Gene
PAPPA
Gene Alias
8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5069
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- ABS 006-24-02 detects native Pregnancy-associated plasma protein A (PAPP-A) from human samples
- Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A
- ABS 006-24-02 has been successfully used in Western blotting, Immunohistochemistry and ELISA procedures
- By Western blot, only unreduced forms of PAPA-A can be detected
- In sandwich ELISA the optimal combination was BTE 004-09-02 as coating and biotinylated ABS 006-24-02 as detection
- ABS 006-24-02 give the strongest singal in IHC compared to ABS 006-01-02 and BTE 004-09-02
- The epitope of ABS 006-24-02 is different from BTE 004-09-02 and ABS 006-01-02
- The epitope is located on the PAPP-A subunit of the heterotetramer
- NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women
- The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits
- Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).