Glucagon Monoclonal Antibody (08), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS0580802-Each-of-1 | In Stock | ₹ 1,22,464.00 |
ABS0580802 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,464.00
GST (18%): ₹ 22,043.52
Total Price: ₹ 1,44,507.52
Antigen
Glucagon
Classification
Monoclonal
Concentration
0.93 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P01274, P01275, P06883
Gene Symbols
Gcg
Immunogen
Synthetic N-terminal fragment of glucagon coupled to carrier.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Porcine, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA
Clone
08
Conjugate
Unconjugated
Gene
Gcg
Gene Alias
GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; IL12p35; IL12P40; Incretin hormone; OXM; OXY; Oxyntomodulin; porcine proglucagon; PPG; preproglucagon; proglucagon
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
24952, 2641, 397595
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- Reactivity: ABS 058-08-02 binds free glucagon in solution
- ABS 058-08-02 can be used as a detection antibody in a sandwich ELISA with capture antibody ABS 061-09-02
- NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL Glucagon is a 29-residue polypeptide hormone (MW 3482), produced in the pancreas
- A related hormone, enteroglucagon (or oxyntomodulin), which is produced in the mucosa of the small and large intestine, consists of the 29 amino acid sequence of pancreatic glucagon extended by 8 additional residues at the C-terminus
- The biological activities of pancreatic glucagon include glycogenolysis, lipolysis, gluconeogenesis, and ketogensis, which are antagonistic effects to those of insulin action, thus leading to increased blood glucose levels
- Immunocytochemical studies have revealed the presence of pancreatic glucagon inside the A or alpha cells, which constitute 15-20% of the islet cell population
- These cells are located preferentially at the periphery of the human pancreatic islets
- Pathological manifestations of the glucagon-type peptide residue almost exclusively with the exsistence of tumors or glucagonomas, as no states of glucagon-cell deficiency or hyperplasia have been identified
- Glucagon-specific antibodies would prove useful as a cell and tumor markers applying immunohistochemical techniques, and as an analytical tool in qualification of the hormone.