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AHB0052

Oligomer A11 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 AHB0052-Each-of-1 In Stock ₹ 39,694.00

AHB0052 - Each of 1

₹ 39,694.00

In Stock

Quantity

1

Base Price: ₹ 39,694.00

GST (18%): ₹ 7,144.92

Total Price: ₹ 46,838.92

Antigen

Oligomer A11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

INS

Gene Alias

Antioligomer A11; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; Insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

16333, 24505, 3630

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Dot Blot, ELISA, Immunohistochemistry, Neutralization, Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

P01308, P01322, P01325

Gene Symbols

INS, Ins1

Immunogen

Synthetic molecular mimic of soluble oligomers.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • This antibody recognizes amino acid sequence-independent oligomers of proteins or peptides
  • A11 does not recognize monomers or mature fibers of proteins or peptides
  • A11 reacts with soluble AB42 oligomers and does not react with soluble low molecular weight AB40 or AB40 fibrils
  • A11 recognizes oligomeric species of several other amyloidogenic polypeptides including AB42, human insulin, prion, polyglutamine, lysozyme, alpha-synuclein and yeast prion Sup35
  • Oligomeric AB42 is recommended as a positive control, monomeric and fibrillar AB42 as negative controls
  • Many degenerative diseases are known to be related to the accumulation of misfolded proteins called, amyloid fibrils
  • Soluble amyloid oligomers are considered as the principal pathogenic species which play an important role in the formation of amyloid fibrils; therefore, oligomers are involved in the pathogenesis of the many neurodegenerative diseases
  • This anti-oligomer antibody provides a facile means of assessing the significance of oligomers in disease pathogenesis.