Home Products Antibodies Primary Antibodies AHB0261
AHB0261

alpha Synuclein Monoclonal Antibody (Syn 211), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 AHB0261-Each-of-1 In Stock ₹ 44,500.00

AHB0261 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

alpha Synuclein

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.

P37840

Gene Symbols

SNCA

Immunogen

Recombinant human alpha-synuclein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

Syn 211

Conjugate

Unconjugated

Gene

SNCA

Gene Alias

Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

6622

Content And Storage

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form

Liquid

Description

  • A suggested positive control for this product is SHSY-5Y cells
  • It will not cross-react with mouse or rat
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
  • These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
  • Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
  • Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
  • Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
  • Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
  • Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.