AMS500
Phosphatidylinositol 4,5-bisphosphate Monoclonal Antibody (2C11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AMS500-Each-of-1 | In Stock | ₹ 48,683.00 |
AMS500 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,683.00
GST (18%): ₹ 8,762.94
Total Price: ₹ 57,445.94
Antigen
Phosphatidylinositol 4,5-bisphosphate
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Target Molecule
Chemical
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
2C11
Conjugate
Unconjugated
Gene Alias
C45H85O19P3; PIP2
Immunogen
Liposomes (prepared in PBS with lipid A, phosphatidylcholine (PC) and cholesterol) containing synthetic di-palmitoyl PtdIns(4,5)P2.
Regulatory Status
RUO
Target Species
Chemical
Product Type
Antibody
Isotype
IgM
Related Products
Description
- MA3-500 detects PIP2 from human tissues
- MA3-500 has been successfully used in ELISA, Immunoprecipitation, Immunofluorescence, and Western blotting procedures
- The MA3-500 antigen is liposomes containing synthetic di-palmitoyl ptdlns(4,5)P2
- Phosphatidylinositol 4,5-bisphosphate or PIP2 is an important second messenger for a number of signaling processes
- When certain extracellular signals are received, Phosphilipase C cleaves phosphatidylinositol into DAG and PIP2
- PIP2 has been shown to interact with actin structural proteins including profiling, gelsolin, and cofilin, and demonstrates regulatory function of actin polymerization
- It has also been shown to regulate vesicular transport by interacting with proteins like ADP-ribosylation factor and phospholipase D
- PIP2 has also been shown to significantly affect intracellular calcium concentrations, which also regulate a variety of activities.