LIMP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APSA6802-Each-of-1 | In Stock | ₹ 49,261.50 |
APSA6802 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,261.50
GST (18%): ₹ 8,867.07
Total Price: ₹ 58,128.57
Antigen
LIMP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SCARB2
Gene Alias
85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AMRF; CD 36; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 2; CD36 molecule; Cd36l2; EPM4; HLGP85; I79_021583; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; Lysosome membrane protein 2; lysosome membrane protein II; MLGP85; Scarb2; Scavenger receptor class B member 2; scavenger receptor class B, member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2; SR-BII
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.05% sodium azide
Gene Accession No.
O35114, P27615, Q14108
Gene Symbols
SCARB2
Immunogen
A C-terminal synthetic peptide made to the mouse LIMPII/lgp85 protein sequence.
Regulatory Status
RUO
Gene ID (Entrez)
117106, 12492, 478435, 950
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- Suggested positive control: 3T3 whole cell lysate
- High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis
- SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene
- SR-BII differs from SR-BI in that the encoded c-terminal cytoplasmic domain is almost completely different
- SR-BII binds HDLs and mediates selective uptake of HDL cholesteryl ester, but with an approximately 4-fold lower efficiency than SR-BI
- Nuclease protection assays show SR-BII to be abundant in mouse tissues expressing SR-BI, with SR-BII expression found in liver, adrenal glands, and testes
- Although the role of SR-BII is not completely clear, research suggests that it may be a functional HDL receptor
- In addition, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with the SR-BII isoform mediating selective transfer of lipid between HDL and cells
- The relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.