Home Products Antibodies Primary Antibodies ASC0104
ASC0104

IL-10 Monoclonal Antibody (945A4C437B1), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 ASC0104-Each-of-1 In Stock ₹ 38,270.00

ASC0104 - Each of 1

₹ 38,270.00

In Stock

Quantity

1

Base Price: ₹ 38,270.00

GST (18%): ₹ 6,888.60

Total Price: ₹ 45,158.60

Antigen

IL-10

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

Q29055

Gene Symbols

IL10

Immunogen

Recombinant swine IL-10.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Porcine

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA

Clone

945A4C437B1

Conjugate

Unconjugated

Gene

IL10

Gene Alias

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

397106

Content And Storage

-20°C

Form

Liquid

Description

  • IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
  • This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
  • It also enhances B cell survival, proliferation, and antibody production
  • Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
  • Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
  • Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
  • Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.