BDB340477
CD154 Mouse anti-Human, PE, Clone: 89-76, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB340477-Each-of-1 | In Stock | ₹ 30,438.00 |
BDB340477 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,438.00
GST (18%): ₹ 5,478.84
Total Price: ₹ 35,916.84
Antigen
CD154
Classification
Monoclonal
Concentration
12.5μg/mL
Formulation
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen
Activiate human peripheral blood lymphocytes (PBLs)
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications
Flow Cytometry
Clone
89-76
Conjugate
PE
Host Species
Mouse
Quantity
50 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- CD154, clone 89-76, is derived from hybridization of mouse NS-1 cells with spleen cells from BALB/c mice immunized with sgp39-CD8 and activated human peripheral blood lymphocytes (PBLs)
- CD154 (CD40 ligand or CD40L) recognizes a 39-kilodalton (kDa) antigen that is a member of the tumor necrosis factor (TNF) receptor family
- CD154 is transiently expressed on activated CD4 T lymphocytes
- The expression of CD154 by activated T-helper cells triggers B-cell cycling through binding to CD40
- This co-receptor interaction is required for B-lymphocyte maturation, response to T-dependent ligands, and isotype switching
- T-lymphocyte proliferation and generation of cytotoxic T lymphocytes (CTLs) is associated with the presence of CD154
- Defects in the CD154 gene are associated with the X-linked hyper IgM syndrome.