BDB550007
IL-1β Mouse anti-Human, Unlabeled, Clone: AS10, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB550007-Each-of-1 | In Stock | ₹ 32,040.00 |
BDB550007 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
IL-1β
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Recombinant human IL-1β
Quantity
0.25 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Immunocytochemistry
Clone
AS10
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- The AS10 antibody reacts with human interleukin-1β (IL-1β) which is also known as endogenous pyrogen (EP), leukocyte endogenous mediator (LEM), mononuclear cell factor (MCF) and lymphocyte-activating factor (LAF)
- IL-1β is a proinflammatory cytokine that is synthesized as a precursor of 31kDa and is converted intracellularly to the mature 17.5kDa form, after cleavage by the IL-1β-converting enzyme (ICE)
- In healthy individuals, IL-1β is secreted non-constitutively by blood monocytes, tissue macrophages and dendritic cells
- IL-1β is also constitutively expressed in the human hypothalamus
- Many malignant tumors express IL-1β as part of their neoplastic nature
- The immunogen used to generate the AS10 hybridoma was recombinant human E
- Coli-expressed recombinant IL-1β
- The AS10 antibody does not cross react with mouse IL-1β
- This is a neutralizing antibody.