BDB550287
CD54 Hamster anti-Mouse, Unlabeled, Clone: 3E2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB550287-Each-of-1 | In Stock | ₹ 18,512.00 |
BDB550287 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,512.00
GST (18%): ₹ 3,332.16
Total Price: ₹ 21,844.16
Antigen
CD54
Classification
Monoclonal
Concentration
125μg/mL
Description
ICAM-1; Icam1; Intercellular adhesion molecule 1; Ly-47; MALA-2; MyD10
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
3.00E+02
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Immunogen
Not reported
Quantity
1 mL
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG1 κ
Related Products
Description
- The 3E2 antibody reacts with CD54 (ICAM-1), a 95kDa member of the Ig superfamily found on lymphocytes, vascular endothelium, high endothelial venules, epithelial cells, macrophages, and dendritic cells
- ICAM-1 is a ligand for LFA1 (CD11a/CD18) and Mac-1 (CD11b/CD18)
- Its expression is upregulated upon stimulation by inflammatory mediators such as cytokines and LPS
- Studies with mouse Icam1-transfected antigen-presenting cells, with CD54-blocking antibodies, and in CD54-deficient mice indicate that CD54 participates in inflammatory reactions and antigen-specific immune responses
- In addition, there is evidence that CD54 is a receptor involved in MHC-non-restricted responses to weakly immunogenic tumor cells
- The 3E2 antibody has been reported to block in vitro and in vivo intracellular adhesion events involved in immune responses.