BDB550295

CD3 Mouse anti-Rat, Unlabeled, Clone: G4.18, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB550295-Each-of-1 In Stock ₹ 18,156.00

BDB550295 - Each of 1

₹ 18,156.00

In Stock

Quantity

1

Base Price: ₹ 18,156.00

GST (18%): ₹ 3,268.08

Total Price: ₹ 21,424.08

Antigen

CD3

Classification

Monoclonal

Concentration

31.25μg/mL

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, goat serum, and ≤ 0.09% sodium azide.

Immunogen

PHA-stimulated rat lymph node and spleen cells

Quantity

1 mL

Research Discipline

Immunology

Target Species

Rat

Isotype

IgG3 κ

Applications

Flow Cytometry

Clone

G4.18

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells
  • It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells
  • In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance
  • Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat
  • No
  • 556970), blocks staining with mAb G4.18.