BDB550493
CD88 Mouse anti-Human, Unlabeled, Clone: D53-1473, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB550493-Each-of-1 | In Stock | ₹ 14,596.00 |
BDB550493 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,596.00
GST (18%): ₹ 2,627.28
Total Price: ₹ 17,223.28
Antigen
CD88
Classification
Monoclonal
Concentration
0.5mg/mL
Description
C5a Receptor
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
D53-1473
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Reacts with a 40kDa polypeptide expressed on granulocytes, monocytes and macrophages
- CD88 is a G type protein-coupled receptor with seven transmembrane domains
- It binds to C5a, the α chain of the complement component C5
- C5a is cleaved from C5 during complement activation
- The binding of C5a to C5a receptor (C5aR, CD88) on granulocytes leads to various effects including shedding of selectins, upregulation of adhesion molecules, chemotaxis, granule exocytosis and activation of NADPH oxidase
- Clone D53-1473 was developed using a known C5aR N-terminal extracellular hydrophilic region (a.a
- 1-31) peptide as immunogen
- This antibody is useful in inflammation and chemotaxis research
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: D53-1473 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry, Immunofluorescence