BDB550539

CD45 Rat anti-Mouse, Unlabeled, Clone: 30-F11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB550539-Each-of-1 In Stock ₹ 18,245.00

BDB550539 - Each of 1

₹ 18,245.00

In Stock

Quantity

1

Base Price: ₹ 18,245.00

GST (18%): ₹ 3,284.10

Total Price: ₹ 21,529.10

Antigen

CD45

Classification

Monoclonal

Concentration

62.5μg/mL

Description

Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

30-F11

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.

Immunogen

Mouse Thymus / Spleen

Quantity

1 mL

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The 30-F11 antibody reacts with both alloantigens and all isoforms of the CD45 leukocytes common antigen (LCA), also known as Ly-5 or T200, found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes
  • CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells
  • CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation
  • The CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific
  • The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.