BDB550978
CD161a Mouse anti-Rat, Biotin, Clone: 10/78, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB550978-Each-of-1 | In Stock | ₹ 16,732.00 |
BDB550978 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,732.00
GST (18%): ₹ 3,011.76
Total Price: ₹ 19,743.76
Antigen
CD161a
Classification
Monoclonal
Concentration
0.5mg/mL
Description
NKR-P1A
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
Oct-78
Conjugate
Biotin
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Not reported
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG1 κ
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Description
- The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T lymphocytes
- The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen
- NKR-P1A is a type-II integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells
- Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity
- NKR-P1A has also been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a subpopulation of large monocytes with phagocytic capacity
- Furthermore, activated peripheral blood neutrophils may express a low level of NKR-P1A
- In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single NKR-P1 homologue has been discovered and designated Cd161