BDB551303
CD8a Mouse anti-Pig, FITC, Clone: 76-2-11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551303-Each-of-1 | In Stock | ₹ 25,632.00 |
BDB551303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,632.00
GST (18%): ₹ 4,613.76
Total Price: ₹ 30,245.76
Antigen
CD8a
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
dd miniature swine thymocytes
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Porcine
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
76-2-11
Conjugate
FITC
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 76-2-11 (also known as clone PT8) antibody reacts with an epitope on the CD8α chain, a 35kDa antigen expressed on thymocytes, peripheral T lymphocytes, and NK cells
- The CD8 molecule can exist as a 70kDa homodimer, composed of α chains, or heterodimer, composed of an α and β chain
- Cells which express the CD8αα homodimer display dimmer staining with mAb 76-2-11 than CDαβ-expressing cells
- The 76-2-11 mAb does not cross-react with human or bovine cells
- Two peripheral CD8+ T-cell populations can be distinguished in the pig: CD8-bright CD4- CTL effectors/precursors and CD8-dull CD4+ T-helper lymphocytes
- Pig NK cells express CD8 (dull staining), CD2, MHC class II, LFA-1, and asialo-GM1, but not CD3, CD4, CD5, or CD6
- mAb 76-2-11 has been reported to partially inhibit in vitro cytotoxic activity of PBL to allogeneic leukocytes, but not NK-cell-mediated lysis, and to deplete CD8+ T cells in vivo
- This clone was clustered as anti-CD8a at the First International Swine CD workshop
- Host Species: Mouse Clone: 76-2-11 Isotype: IgG2a κ Species Reactivity: Porcine Immunogen: dd miniature swine thymocytes Flow Cytometry