BDB551796

Fetal Hemoglobin Mouse anti-Human, Unlabeled, Clone: 2D12, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB551796-Each-of-1 In Stock ₹ 20,470.00

BDB551796 - Each of 1

₹ 20,470.00

In Stock

Quantity

1

Base Price: ₹ 20,470.00

GST (18%): ₹ 3,684.60

Total Price: ₹ 24,154.60

Antigen

Fetal Hemoglobin

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

2D12

Conjugate

Unconjugated

Host Species

Mouse

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG1 κ

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Description

  • Reacts with fetal hemoglobin (HbF), a form of hemoglobin present during fetal development
  • HbF resembles adult hemoglobin (HbA) in possessing two alpha chains but differs in possessing two gamma instead of two beta chains
  • In normal adults, synthesis of HbF does persist at very low levels (<1% of total Hb) and is restricted to a small population of erythrocytes called F cells
  • Hemoglobin F-expressing erythrocytes are normally seen during pregnancy
  • An increase in the expression of fetal hemoglobin in adult peripheral red blood cells is a common feature in the genetic disorders of hemoglobin, sickle-cell disease (SCD) and beta thalassemia
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: 2D12 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry, Intracellular Staining