BDB551900
CD32 Mouse anti-Human, Unlabeled, Clone: 3D3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551900-Each-of-1 | In Stock | ₹ 15,486.00 |
BDB551900 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,486.00
GST (18%): ₹ 2,787.48
Total Price: ₹ 18,273.48
Antigen
CD32
Classification
Monoclonal
Concentration
0.5mg/mL
Description
FcγRII
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
3D3
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Reacts with FcγRII (CD32), a 40 kDa, polymorphic transmembranous glycoprotein, highly glycosylated molecule (encoded by at least two genes), expressed on monocytes, granulocytes, platelets and B cells
- Unlike FLI28.6, 3D3 mAb detected a polymorphic CD32 antigen expressed on B cells of all donors, but only on platelets, monocytes and granulocytes of some donors
- The platelets from 3D3+ donors respond to certain stimulatory mAb such as CD165 (clone SN2, Cat
- No
- 556050) and result in aggregation
- On the other hand, the platelets from 3D3 negative donors do not form aggregates after stimulation
- Individuals can be divided into two groups as responder and non-responder depending on expression, or non-expression, of 3D3
- In comparison to 3D3, FLI8.26 detects a monomorphic CD32 antigen expressed on all human donors
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.