BDB552146
CD278 Rat anti-Mouse, PE, Clone: 7E.17G9, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552146-Each-of-1 | In Stock | ₹ 32,040.00 |
BDB552146 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
CD278
Classification
Monoclonal
Concentration
0.2mg/mL
Description
ICOS; Ailim; CCLP; CRP-1; Ly115; Inducible T-cell costimulator
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
7E.17G9
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse Icos cDNA and ICOS hexahistidine fusion protein
Quantity
0.2 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b κ
Related Products
Description
- The 7E.17G9 antibody reacts with CD278, the I nducible Cos timulatory molecule (ICOS), a 47-57 kDa homodimeric glycoprotein of the CD28 family of costimulatory molecules
- ICOS is expressed on subpopulations of CD4-CD8- and CD4+CD8- (but not CD4-CD8+ or CD4+CD8+) thymocytes, on some T-cell lines, and on small numbers of peripheral leukocytes
- It is upregulated on T lymphocytes following activation via the T-cell receptor
- The T-cell activation marker H4 is the same molecule asICOS
- ICOS is a costimulatory receptor, and its ligand on antigen-presenting cells has been called B7RP-1, GL50, B7h, B7-H2, or LICOS
- There is considerable evidence that the interaction of ICOS with its ligand is involved in the regulation of many, but not all, T-cell-mediated immune responses.