BDB552298
CD172 Mouse anti-Rat, PE, Clone: OX-41, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552298-Each-of-1 | In Stock | ₹ 16,198.00 |
BDB552298 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,198.00
GST (18%): ₹ 2,915.64
Total Price: ₹ 19,113.64
Antigen
CD172
Classification
Monoclonal
Concentration
0.2mg/mL
Description
SIRP
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
OX-41
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Resident peritoneal cells from cross-bred rat strains
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG2a κ
Related Products
Description
- Description The OX-41 antibody reacts with the rat signal-regulatory protein (SIRP)
- The rat SIRP (CD172) is a 110-120-kDa type 1 transmembrane protein with three extracellular immunoglobulin superfamily domains and two intracellular I mmunoreceptor T yrosinebased M otifs (ITIM)
- The SIRP ITIMs are phosphorylated in response to activation by growth hormone, epidermal growth factor, and integrin-mediated cell adhesion
- The phosphorylated SIRP associates with tyrosine phosphatases SHP-1 and/or SHP-2
- In the rat, SIRP is selectively expressed on myeloid cells (monocytes, macrophages, granulocytes, and dendritic cells) and neurons
- The ligand for rat SIRP is CD47, which is similar to the interaction of the human homolog SIRP α 1 (CD172 α ) and human CD47
- The SIRP/CD47 interaction is thought to be important in maintaining cellular adhesion and possibly promote T-cell activation.