BDB552602
CD172b Mouse anti-Human, PE, Clone: B4B6, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552602-Each-of-1 | In Stock | ₹ 29,548.00 |
BDB552602 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,548.00
GST (18%): ₹ 5,318.64
Total Price: ₹ 34,866.64
Antigen
CD172b
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human SIRPβ1 extracellular domain Recombinant Protein
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
B4B6
Description
SIRPB1; SIRP-BETA-1; SIRPβ1; SIRPbeta; SIRP beta
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- Reacts with a 50 kDa, type I transmembrane glycoprotein known as signal regulatory protein β (SIRPβ)
- The SIRPs are members of the immunoglobulin superfamily
- SIRPβ does not possess a cytoplasmic domain but instead the transmembrane domain contains a positively-charged residue that interacts with one other transmembrane protein (DAP-12 or KARAP)
- DAP-12 has two immunoreceptor tyrosine-based activation motifs (ITAM) within its cytoplasmic domain that are thought to link SIRPβ to activating machinery
- SIRPβ is expressed on peripheral blood monocytes and granulocytes, but is not expressed on CD34+ cells
- SIRPα and SIRPβ have complementary roles in signal regulation and may work together in tuning the response to a stimulus