BDB552853
CD127 Mouse anti-Human, Unlabeled, Clone: HIL-7R-M21, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552853-Each-of-1 | In Stock | ₹ 13,590.30 |
BDB552853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,590.30
GST (18%): ₹ 2,446.254
Total Price: ₹ 16,036.554
Antigen
CD127
Classification
Monoclonal
Concentration
0.5mg/mL
Description
IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
HIL-7R-M21
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human IL-7R Recombinant Protein
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The hIL-7R-M21 monoclonal antibody specifically binds to the 60-90 kDa glycoprotein, CD127
- CD127 is also known as the IL-7 receptor alpha (IL-7R α ) subunit
- The IL-7 receptor complex is a heterodimer composed of CD127 and the common gamma chain ( γc, CD132), shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, IL-15R, and IL-21R)
- CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells
- In vitro experiments show the expression of CD127 is down-regulated following T cell activation
- Studies indicate that the IL-7 Receptor plays an important role in the proliferation and differentiation of mature T cells
- Recently, it has been shown that low surface expression of CD127, in combination with intermediate to high surface expression of CD25, the α chain of the IL-2 receptor complex, can distinguish between human regulatory and conventional CD4+ T cells in human adult and cord blood, lymph nodes and thymus.