BDB552857
VEGFR-3 Rat anti-Mouse, Unlabeled, Clone: AFL4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552857-Each-of-1 | In Stock | ₹ 18,601.00 |
BDB552857 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,601.00
GST (18%): ₹ 3,348.18
Total Price: ₹ 21,949.18
Antigen
VEGFR-3
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Immunohistochemistry (Paraffin)
Clone
AFL4
Formulation
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Immunogen
VEGFR-3 extracellular domain
Quantity
1 mL
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The AFL4 antibody reacts with mouse VEGFR-3, an endothelial-specific receptor tyrosine kinase (RTK) related to VEGF receptors
- The immunogen used was the extracellular domain of VEGFR-3, corresponding to nucleotides 45-2354 in the GeneBank L07296
- VEGFR-3 is induced in all endothelial cells (ECα) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues
- VEGFR-3 is constitutively expressed in the adult lymphatic endothelium
- Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues
- Studies have shown that both VEGF-C and VEGF-D, ligands for VEGFR-3, promote lymphatic vessel proliferation throughout central tumor areas and at their peripheries, demonstrating that such molecules aid in the spread of tumor cells from the primary tumor to local lymph nodes
- Host Species: Rat Clone: AFL4 Isotype: IgG2a κ Species Reactivity: Mouse Immunogen: VEGFR-3 extracellular domain Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blotting