BDB552866
NKG2D Mouse anti-Human, Unlabeled, Clone: 1D11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552866-Each-of-1 | In Stock | ₹ 15,548.30 |
BDB552866 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,548.30
GST (18%): ₹ 2,798.694
Total Price: ₹ 18,346.994
Antigen
NKG2D
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
NKL cells
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
1D11
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Antibody 1D11 reacts with NKG2D (42kDa), an activating receptor for MICA encoded within MHC
- Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells, it is also present on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
- NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
- More importantly, NKG2D can complement the role of NCR in tumor cell lysis
- Remarkably, the combined maskings of NCR and NKG2D led to a complete inhibition of NK-mediated lysis of all tumor or normal cells
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 1D11 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry