BDB552884

CD32 Mouse anti-Human, PE, Clone: 3D3, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB552884-Each-of-1 In Stock ₹ 29,325.50

BDB552884 - Each of 1

₹ 29,325.50

In Stock

Quantity

1

Base Price: ₹ 29,325.50

GST (18%): ₹ 5,278.59

Total Price: ₹ 34,604.09

Antigen

CD32

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

3D3

Description

FcγRII

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • Reacts with FcγRII (CD32), a 40 kDa, polymorphic transmembranous glycoprotein, highly glycosylated molecule (encoded by at least two genes), expressed on monocytes, granulocytes, platelets and B cells
  • Unlike FLI28.6, 3D3 mAb detected a polymorphic CD32 antigen expressed on B cells of all donors, but only on platelets, monocytes and granulocytes of some donors
  • The platelets from 3D3+ donors respond to certain stimulatory mAb such as CD165 (clone SN2, Cat
  • No
  • 556050) and result in aggregation
  • On the other hand, the platelets from 3D3 negative donors do not form aggregates after stimulation
  • Individuals can be divided into two groups as responder and non-responder depending on expression, or non-expression, of 3D3
  • In comparison to 3D3, FLI8.26 detects a monomorphic CD32 antigen expressed on all human donors.