BDB553373
CD31 Rat anti-Mouse, PE, Clone: MEC 13.3, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553373-Each-of-1 | In Stock | ₹ 30,616.00 |
BDB553373 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,616.00
GST (18%): ₹ 5,510.88
Total Price: ₹ 36,126.88
Antigen
CD31
Classification
Monoclonal
Concentration
0.2mg/mL
Description
PECAM-1
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MEC 13.3
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
129/Sv mouse-derived endothelioma cell line tEnd.1
Quantity
0.2 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The MEC13.3 antibody reacts with CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1)
- CD31 is a 130 kDa integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion
- CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is also expressed on many peripheral leukocytes and platelets
- It has also been detected on bone marrow-derived hematopoietic stem cells and embryonic stem cells
- CD31 is involved in the transendothelial emigration of neutrophils, and neutrophil PECAM-1 appears to be down-regulated after extravasation into inflamed tissues
- Multiple alternatively spliced isoforms are detected during early post-implantation embryonic development; this alternative splicing is involved in the regulation of ligand specificity
- CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31
- CD31-mediated endothelial cell-cell interactions are involved in angiogenesis
- The MEC13.3 mAb inhibits a variety of in vitro and in vivo functions mediated by CD31.