BDB553730
CD4 Rat anti-Mouse, PE, Clone: GK1.5, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553730-Each-of-1 | In Stock | ₹ 11,392.00 |
BDB553730 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,392.00
GST (18%): ₹ 2,050.56
Total Price: ₹ 13,442.56
Antigen
CD4
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
GK1.5
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CTL clone V4
Quantity
0.2 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b κ
Related Products
Description
- The GK1.5 monoclonal antibody specifically binds to the mouse CD4 (L3T4) differentiation antigen
- CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells
- In addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
- CD4 has also been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
- CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
- It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
- The GK1.5 antibody reportedly blocks binding of the RM4-5 and H129.19, but not RM4-4 mouse CD4-specific antibodies.