BDB553845

CD1d Rat anti-Mouse, FITC, Clone: 1B1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB553845-Each-of-1 In Stock ₹ 40,762.00

BDB553845 - Each of 1

₹ 40,762.00

In Stock

Quantity

1

Base Price: ₹ 40,762.00

GST (18%): ₹ 7,337.16

Total Price: ₹ 48,099.16

Antigen

CD1d

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Cd1d1; Cd1.1; Cd1a; Cd1d; Ly-38

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

1B1

Conjugate

FITC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma and mouse L929 cells

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The 1B1 monoclonal antibody specifically binds to mouse CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I molecules
  • The structure, expression, and functions of CD1 antigens are complex and have been reviewed
  • mAb 1B1 detects CD1d at varying levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus
  • It appears to recognize CD1d only in association with β2m
  • CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the cytoplasm of hepatocytes as detected via immunohistochemical staining of frozen sections with mAb 3C11 (Cat
  • No
  • 559871, for the purified antibody), suggesting a possible role for CD1d in mucosal immunity
  • However, CD1d expression was not detectable, via flow cytometry, on intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1, and 9C7
  • The 1B1 antibody competes with mAb 3C11 in binding to mouse splenocytes.