BDB554069
p27 (Kip1) Mouse, Unlabeled, Clone: G173-524, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554069-Each-of-1 | In Stock | ₹ 32,173.50 |
BDB554069 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,173.50
GST (18%): ₹ 5,791.23
Total Price: ₹ 37,964.73
Antigen
p27 (Kip1)
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse p27 [Kip1] (full-length) Recombinant Protein
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1
Applications
Western Blot
Clone
G173-524
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Related Products
Description
- Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes
- Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle
- These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes
- These include p15, p16, p18, p19, p21 and p27 [Kip1]
- p27 [Kip1] has been shown to inhibit the activity of multiple cyclin-cdk complexes, including cyclin D-cdk4, cyclin E-cdk2 and cyclin A-cdk2
- p27 [Kip1] is a 27kDa protein which shares N-terminal sequence homology with p21, and like p21, p27 [Kip1] contains a nuclear localization signal in its C-terminal region
- IL-2 activation of T cells has been reported to lead to a decrease in p27 [Kip1] and entry into S phase
- Removal of IL-2 from T cell cultures results in increased levels of p27 [Kip1] and cell quiescence
- Host Species: Mouse Clone: G173-524 Isotype: IgG1 Species Reactivity: Mouse Immunogen: Mouse p27 [Kip1] (full-length) Recombinant Protein Formula Weight [Chemical]: 27kDa Bioimaging, Immunoprecipitation, Western Blotting