BDB554428

IL-2 Rat anti-Mouse, PE, Clone: JES6-5H4, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554428-Each-of-1 In Stock ₹ 27,367.50

BDB554428 - Each of 1

₹ 27,367.50

In Stock

Quantity

1

Base Price: ₹ 27,367.50

GST (18%): ₹ 4,926.15

Total Price: ₹ 32,293.65

Antigen

IL-2

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Recombinant mouse IL-2

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b

Applications

Flow Cytometry

Clone

JES6-5H4

Conjugate

PE

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Description The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2)
  • IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance
  • It is produced by activated T cells
  • IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages
  • IL-2 mediates its biological activities by binding to IL-2 receptor compleses
  • The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits
  • The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.