BDB554841
CD4 Mouse anti-Rat, Unlabeled, Clone: OX-38, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554841-Each-of-1 | In Stock | ₹ 23,273.50 |
BDB554841 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,273.50
GST (18%): ₹ 4,189.23
Total Price: ₹ 27,462.73
Antigen
CD4
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat thymocyte glycoproteins
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
OX-38
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- The OX-38 antibody has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, and some dendritic cells
- CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
- It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
- The OX-38 antibody has been reported to bind to the same epitope of CD4 as that recognized by W3/25 mAb, which is a different epitope than that recognized by OX-35 mAb (Cat
- No
- 554837)
- In vivo blocking of some cell-mediated immune responses by mAb OX-38 has been reported
- Injection of OX-38 mAb induces allograft unresponsiveness in rats, with varying results depending on the rat strain used (high or low responder)
- Furthermore, in vivo depletion of CD4+ lymphocytes has been reported with this antibody
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.