BDB555018

CD86 Mouse anti-Rat, FITC, Clone: 24F, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555018-Each-of-1 In Stock ₹ 34,176.00

BDB555018 - Each of 1

₹ 34,176.00

In Stock

Quantity

1

Base Price: ₹ 34,176.00

GST (18%): ₹ 6,151.68

Total Price: ₹ 40,327.68

Antigen

CD86

Classification

Monoclonal

Concentration

0.5mg/mL

Description

B7-2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

24F

Conjugate

FITC

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

HTLV-1-transformed rat T-cell line Lewis-S1

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Rat

Isotype

IgG1 κ

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Description

  • The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins
  • CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions
  • CD86 is predominantly expressed on antigen-presenting cells
  • It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment
  • 24F mAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates.HTLV-1-transformed rat T-cell line Lewis-S1 This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.