BDB555273
CD3 Molecular Complex Rat anti-Mouse, Unlabeled, Clone: 17A2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555273-Each-of-1 | In Stock | ₹ 22,161.00 |
BDB555273 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,161.00
GST (18%): ₹ 3,988.98
Total Price: ₹ 26,149.98
Antigen
CD3 Molecular Complex
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
γδ TCR-positive T-T hybridoma D1
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
17A2
Conjugate
Unconjugated
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
- Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
- The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11
- This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
- In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.