BDB555298

CD47 Rat anti-Mouse, FITC, Clone: MIAP301, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555298-Each-of-1 In Stock ₹ 35,422.00

BDB555298 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD47

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Cd47; IAP; Integrin-associated protein; Itgp

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

MIAP301

Conjugate

FITC

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Not reported

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • The miap301 monoclonal antibody specifically binds to the extracellular domain of CD47, also known as Integrin-Associated Protein (IAP)
  • CD47 is a 50-kDa plasma membrane protein with an extracellular immunoglobulin variable region-like domain, a multiple membrane-spanning segment, and a short C-terminal cytoplasmic tail
  • IAP is often physically associated with β3 integrins, and it may act as a transducer element in activation mediated by these integrins
  • CD47 is expressed by a wide variety of cell types, including some cells lacking integrins, such as erythrocytes
  • The cytoplasmic tail region is expressed as alternatively spliced forms, which are differentially expressed in diverse tissues, suggesting that IAP may have distinct functions in various tissues
  • CD47 and its ligand, CD172a, are proposed to mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages.