BDB555317

CD74 Rat anti-Mouse, Unlabeled, Clone: IN-1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555317-Each-of-1 In Stock ₹ 34,710.00

BDB555317 - Each of 1

₹ 34,710.00

In Stock

Quantity

1

Base Price: ₹ 34,710.00

GST (18%): ₹ 6,247.80

Total Price: ₹ 40,957.80

Antigen

CD74

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Ii

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

IN-1

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

ATL mouse lymphocytes and B10A mouse-derived CH1 B-cell lymphoma

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The In-1 antibody reacts with CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations
  • Although it is predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number of B lymphocytes
  • In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a chondroitin sulfate side chain which allows it to interact with CD44
  • CD74 is directly involved in the intracellular transport of MHC class II molecules and antigen presentation, and it affects the maturation of T and B lymphocytes.