BDB555387
CD11b/Mac-1 Mouse anti-Human, Biotin, Clone: ICRF44, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555387-Each-of-1 | In Stock | ₹ 27,189.50 |
BDB555387 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,189.50
GST (18%): ₹ 4,894.11
Total Price: ₹ 32,083.61
Antigen
CD11b
Classification
Monoclonal
Conjugate
Biotin
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human monocytes
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
ICRF44
Description
Mac-1α, integrin αM subunit, CR3 α chain
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
- CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
- CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
- This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.