BDB555493

CD45RO Mouse anti-Human, PE, Clone: UCHL1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555493-Each-of-1 In Stock ₹ 24,742.00

BDB555493 - Each of 1

₹ 24,742.00

In Stock

Quantity

1

Base Price: ₹ 24,742.00

GST (18%): ₹ 4,453.56

Total Price: ₹ 29,195.56

Antigen

CD45RO

Classification

Monoclonal

Conjugate

PE

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

UCHL1

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human IL-2-dependent T-cell line

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2a κ

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Description

  • The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen)
  • CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways
  • This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C
  • CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells
  • CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations
  • CD45RO binds to CD22.