BDB555590
CD40 Mouse anti-Human, PE-Cy5, Clone: 5C3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555590-Each-of-1 | In Stock | ₹ 33,241.50 |
BDB555590 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,241.50
GST (18%): ₹ 5,983.47
Total Price: ₹ 39,224.97
Antigen
CD40
Classification
Monoclonal
Conjugate
PE-Cyanine5
Host Species
Mouse
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
5C3
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- This 5C3 monoclonal antibody specifically binds to CD40, a 45-48 kDa type I integral membrane glycoprotein
- CD40 is expressed on B lymphocytes, but is not expressed on terminally differentiated B cells
- CD40 is also expressed by endothelial cells, basal epithelial cells and some epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells
- This antibody is useful for studying the roles played by CD40 in B-cell growth, proliferation, and differentiation including immunoglobulin isotype switching
- Anti-CD40 antibodies have been reported to stimulate B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters
- 5C3 is capable of inducing B-cell proliferation when presented with IL-4.