BDB555649
CD62E Mouse anti-Human, Biotin, Clone: 68-5H11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555649-Each-of-1 | In Stock | ₹ 24,920.00 |
BDB555649 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,920.00
GST (18%): ₹ 4,485.60
Total Price: ₹ 29,405.60
Antigen
CD62E
Classification
Monoclonal
Concentration
0.5mg/mL
Description
SELE; E-selectin; Selectin E; ELAM; ELAM1; ESEL; LECAM2
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
68-5H11
Conjugate
Biotin
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 68-5H11 monoclonal antibody specifically binds to CD62E
- This adhesion molecule is a 97-115 kDa type I transmembrane glycoprotein that is encoded by the SELE gene
- CD62E is also known as E-selectin, Endothelial-leukocyte adhesion molecule-1 (ELAM-1), and Leukocyte endothelial cell adhesion molecule 2 (LECAM-2)
- CD62E is minimally expressed by unstimulated endothelium
- Activated endothelial cells upregulate surface CD62E expression in response to various activators including inflammatory cytokines such as Interleukin-1 and Tumor Necrosis Factor
- CD62E plays a role in leucocyte extravasation by promoting leucocyte rolling on activated endothelial cells during inflammation
- CD62E may also play a role in the metastasis of certain tumor cells
- The adhesion between endothelial CD62E molecules and a carbohydrate ligand on neutrophils is inhibited by the mAb 68-5H11.