BDB555662
CD86 Mouse anti-Human, NA/LE, Unlabeled, Clone: IT2.2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555662-Each-of-1 | In Stock | ₹ 53,044.00 |
BDB555662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,044.00
GST (18%): ₹ 9,547.92
Total Price: ₹ 62,591.92
Antigen
CD86
Classification
Monoclonal
Concentration
1.0mg/mL
Description
B70/B7-2
Host Species
Mouse
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
IT2.2
Conjugate
Unconjugated
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Related Products
Description
- IT2.2 recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells including lymphoid cells in germinal centers and Epstein-Barr virus transformed B-cell lines
- CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in costimulation of T cells in primary immune response
- Competitive binding assays demonstrate that, while both IT2.2 and FUN-1 (anti-CD86) recognize the same molecule, they react with different epitopes
- IT2.2 blocks costimulation activity of CD86 in functional studies and blocks binding of human CTLA-4-Ig fusion protein to B70 gene-transfected cells.