BDB555663
CD86 Mouse anti-Human, Unlabeled, Clone: IT2.2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555663-Each-of-1 | In Stock | ₹ 21,716.00 |
BDB555663 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,716.00
GST (18%): ₹ 3,908.88
Total Price: ₹ 25,624.88
Antigen
CD86
Classification
Monoclonal
Concentration
0.5mg/mL
Description
B70/B7-2
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
IT2.2
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- IT2.2 recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells including lymphoid cells in germinal centers and Epstein-Barr virus transformed B-cell lines
- CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in costimulation of T cells in primary immune response
- Competitive binding assays demonstrate that, while both IT2.2 and FUN-1 (anti-CD86) recognize the same molecule, they react with different epitopes
- IT2.2 blocks costimulation activity of CD86 in functional studies and blocks binding of human CTLA-4-Ig fusion protein to B70 gene-transfected cells.