BDB555702

CD154 Mouse anti-Human, APC, Clone: TRAP1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555702-Each-of-1 In Stock ₹ 35,422.00

BDB555702 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD154

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

TRAP1

Description

CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

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Description

  • Reacts with CD40 ligand (CD40L), a 39kDa type II membrane glycoprotein expressed on activated T cells
  • CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation
  • Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation
  • Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells
  • In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching
  • It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: TRAP1 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry