BDB555824

CD34 Mouse anti-Human, APC, Clone: 581, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555824-Each-of-1 In Stock ₹ 32,040.00

BDB555824 - Each of 1

₹ 32,040.00

In Stock

Quantity

1

Base Price: ₹ 32,040.00

GST (18%): ₹ 5,767.20

Total Price: ₹ 37,807.20

Antigen

CD34

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

581

Description

gp105-120; My10; Hematopoietic progenitor cell antigen CD34

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 581 monoclonal antibody specifically binds to CD34, a sialomucin-like type I transmembrane glycoprotein
  • This single-chain, 105-120 kDa, heavily O-glycosylated protein is expressed on hematopoietic progenitor cells, vascular endothelium, bone marrow stromal cells and embryonic fibroblasts
  • The cytoplasmic region of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting CD34 may play a role in signal transduction
  • CD34 may also play a role as an adhesion molecule since it binds to CD62E and CD62L
  • Clone 581 binds to the class III CD34 epitope, it is resistant to neuraminidase, chymopapain and glycoprotease
  • The 581 antibody blocks reactivity of another anti-CD34 monoclonal antibody, 8G12.