BDB555974

CD184 Mouse anti-Human, PE, Clone: 12G5, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555974-Each-of-1 In Stock ₹ 31,639.50

BDB555974 - Each of 1

₹ 31,639.50

In Stock

Quantity

1

Base Price: ₹ 31,639.50

GST (18%): ₹ 5,695.11

Total Price: ₹ 37,334.61

Antigen

CD184

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

SIVmac variant CP-MAC-infected Sup-T1 cells

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

12G5

Description

CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 12G5 monoclonal antibody specifically binds to CD184, also known as CXCR4 and Fusin
  • CD184/CXCR4 is a seven-transmembrane domain, G-protein-linked, glycoprotein chemokine receptor
  • CD184 serves as a receptor for the C-X-C chemokine, SDF-1
  • It is expressed on a wide variety of hematopietic cells, vascular endothelial cells and cells of the nervous system
  • CD184 plays a variety of roles in hematopoiesis, vascularization and neural development
  • CD184 also functions as a coreceptor for infection with T-cell tropic strains of HIV-1 and as a receptor for CD4-independent infection by some HIV isolates
  • The 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.